Bidirectional synaptic structural plasticity after chronic cocaine administration occurs through Rap1 small GTPase signaling

Dendritic spines are the sites of most excitatory synapses in the CNS, and opposing alterations in the synaptic structure of medium spiny neurons (MSNs) of the nucleus accumbens, a primary brain reward region, are seen at early vs. late time points after cocaine administration. Here we investigate t...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Cahill, Michael E., Bagot, Rosemary C., Gancarz, Amy M., Walker, Deena M., Sun, HaoSheng, Wang, Zi-Jun, Heller, Elizabeth A., Feng, Jian, Kennedy, Pamela J., Koo, Ja Wook, Cates, Hannah M., Neve, Rachael L., Shen, Li, Dietz, David M., Nestler, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743039/
https://ncbi.nlm.nih.gov/pubmed/26844834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.01.031
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