Age-Related Increased Prevalence of Asthma and Nasal Polyps in Chronic Rhinosinusitis and Its Association with Altered IL-6 Trans-Signaling

We report that S100 proteins were reduced in patients with chronic rhinosinusitis (CRS). S100A8/9, which is important in epithelial barrier function, was particularly decreased in elderly patients with CRS. Epithelial expression of S100A8/9 is partly regulated by the IL-6 trans-signaling pathway. Th...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Cho, Seong H., Kim, Dae Woo, Lee, Sun H., Kolliputi, Narasaiah, Hong, Seung J., Suh, Lydia, Norton, James, Hulse, Kathryn E., Seshadri, Sudarshan, Conley, David B., Kern, Robert C., Tan, Bruce K., Peters, Anju, Grammer, Leslie C., Schleimer, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Rapid Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742956/
https://ncbi.nlm.nih.gov/pubmed/26266960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0207RC
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