Effects of Combining Rapamycin and Resveratrol on Apoptosis and Growth of TSC2-Deficient Xenograft Tumors

Lymphangioleiomyomatosis (LAM) is a rare neoplastic metastatic disease affecting women of childbearing age. LAM is caused by hyperactivation of the mechanistic target of rapamycin complex 1 (mTORC1) as a consequence of tuberous sclerosis complex (TSC) 1/2 inactivation. Clinically, LAM results in cys...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Alayev, Anya, Salamon, Rachel S., Sun, Yang, Schwartz, Naomi S., Li, Chenggang, Yu, Jane J., Holz, Marina K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742955/
https://ncbi.nlm.nih.gov/pubmed/25844891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0022OC
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