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The Combination of Rapamycin and Resveratrol Blocks Autophagy and Induces Apoptosis in Breast Cancer Cells

Hyperactivation of the mechanistic target of rapamycin complex 1 (mTORC1) is a frequent event in breast cancer and current efforts are aimed at targeting the mTORC1 signaling pathway in combination with other targeted therapies. However, patients often develop drug resistance in part due to activati...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Alayev, Anya, Berger, Sara Malka, Kramer, Melissa Y., Schwartz, Naomi S., Holz, Marina K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491987/
https://ncbi.nlm.nih.gov/pubmed/25336146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24997
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