Regulation of Alveolar Procoagulant Activity and Permeability in Direct Acute Lung Injury by Lung Epithelial Tissue Factor

Tissue factor (TF) initiates the extrinsic coagulation cascade in response to tissue injury, leading to local fibrin deposition. Low levels of TF in mice are associated with increased severity of acute lung injury (ALI) after intratracheal LPS administration. However, the cellular sources of the TF...

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Bibliografische gegevens
Gepubliceerd in:Am J Respir Cell Mol Biol
Hoofdauteurs: Shaver, Ciara M., Grove, Brandon S., Putz, Nathan D., Clune, Jennifer K., Lawson, William E., Carnahan, Robert H., Mackman, Nigel, Ware, Lorraine B., Bastarache, Julie A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Thoracic Society 2015
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742948/
https://ncbi.nlm.nih.gov/pubmed/25884207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0179OC
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