Regulation of Alveolar Procoagulant Activity and Permeability in Direct Acute Lung Injury by Lung Epithelial Tissue Factor

Tissue factor (TF) initiates the extrinsic coagulation cascade in response to tissue injury, leading to local fibrin deposition. Low levels of TF in mice are associated with increased severity of acute lung injury (ALI) after intratracheal LPS administration. However, the cellular sources of the TF...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: Shaver, Ciara M., Grove, Brandon S., Putz, Nathan D., Clune, Jennifer K., Lawson, William E., Carnahan, Robert H., Mackman, Nigel, Ware, Lorraine B., Bastarache, Julie A.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742948/
https://ncbi.nlm.nih.gov/pubmed/25884207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0179OC
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