Regulation of Alveolar Procoagulant Activity and Permeability in Direct Acute Lung Injury by Lung Epithelial Tissue Factor

Tissue factor (TF) initiates the extrinsic coagulation cascade in response to tissue injury, leading to local fibrin deposition. Low levels of TF in mice are associated with increased severity of acute lung injury (ALI) after intratracheal LPS administration. However, the cellular sources of the TF...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Shaver, Ciara M., Grove, Brandon S., Putz, Nathan D., Clune, Jennifer K., Lawson, William E., Carnahan, Robert H., Mackman, Nigel, Ware, Lorraine B., Bastarache, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742948/
https://ncbi.nlm.nih.gov/pubmed/25884207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0179OC
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