Role of Exchange Protein Activated by cAMP 1 in Regulating Rates of Microtubule Formation in Cystic Fibrosis Epithelial Cells

The regulation of microtubule dynamics in cystic fibrosis (CF) epithelial cells and the consequences of reduced rates of microtubule polymerization on downstream CF cellular events, such as cholesterol accumulation, a marker of impaired intracellular transport, are explored here. It is identified th...

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Publicado en:Am J Respir Cell Mol Biol
Autores principales: Rymut, Sharon M., Ivy, Tracy, Corey, Deborah A., Cotton, Calvin U., Burgess, James D., Kelley, Thomas J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2015
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742938/
https://ncbi.nlm.nih.gov/pubmed/25955407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0462OC
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