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Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells

The use of high-dose ibuprofen as an anti-inflammatory therapy in cystic fibrosis (CF) has been shown to be an effective intervention although use is limited due to potential adverse events. Identifying the mechanism of ibuprofen efficacy would aid in the development of new therapies that avoid thes...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Rymut, Sharon M., Lu, Binyu, Perez, Aura, Corey, Deborah A., Lamb, Kata, Cotton, Calvin U., Kelley, Thomas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620671/
https://ncbi.nlm.nih.gov/pubmed/30892081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00369.2018
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