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Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells

The use of high-dose ibuprofen as an anti-inflammatory therapy in cystic fibrosis (CF) has been shown to be an effective intervention although use is limited due to potential adverse events. Identifying the mechanism of ibuprofen efficacy would aid in the development of new therapies that avoid thes...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Rymut, Sharon M., Lu, Binyu, Perez, Aura, Corey, Deborah A., Lamb, Kata, Cotton, Calvin U., Kelley, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620671/
https://ncbi.nlm.nih.gov/pubmed/30892081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00369.2018
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