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Endothelial Dicer promotes atherosclerosis and vascular inflammation by miRNA-103-mediated suppression of KLF4

MicroRNAs regulate the maladaptation of endothelial cells (ECs) to naturally occurring disturbed blood flow at arterial bifurcations resulting in arterial inflammation and atherosclerosis in response to hyperlipidemic stress. Here, we show that reduced endothelial expression of the RNAse Dicer, whic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Hartmann, Petra, Zhou, Zhe, Natarelli, Lucia, Wei, Yuanyuan, Nazari-Jahantigh, Maliheh, Zhu, Mengyu, Grommes, Jochen, Steffens, Sabine, Weber, Christian, Schober, Andreas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742841/
https://ncbi.nlm.nih.gov/pubmed/26837267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10521
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