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Activated mast cells promote differentiation of B cells into effector cells

Based on the known accumulation of mast cells (MCs) in B cell-dependent inflammatory diseases, including rheumatoid arthritis, we hypothesized that MCs directly modulate B cells. We show here that degranulated, and to a lesser extent naïve or IgE-sensitized, MCs activate both naïve and B cell recept...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Palm, Anna-Karin E., Garcia-Faroldi, Gianni, Lundberg, Marcus, Pejler, Gunnar, Kleinau, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742803/
https://ncbi.nlm.nih.gov/pubmed/26847186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20531
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