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Inhibition of the BET family of epigenetic reader proteins: A novel principle for modulating gene expression in IgE‐activated mast cells
INTRODUCTION: The BET family of bromodomain‐containing proteins constitute epigenetic readers that bind to acetylated lysine residues of core histones, thereby translating epigenetic histone marks to effects on gene expression. BET inhibitors are currently emerging as promising therapeutic agents fo...
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| Izdano u: | Immun Inflamm Dis |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5418135/ https://ncbi.nlm.nih.gov/pubmed/28474499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.150 |
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