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The Sensorless Pore Module of Voltage-gated K(+) Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine
KCNQ (voltage-gated K(+) channel family 7 (Kv7)) channels control cellular excitability and underlie the K(+) current sensitive to muscarinic receptor signaling (the M current) in sympathetic neurons. Here we show that the novel anti-epileptic drug retigabine (RTG) modulates channel function of pore...
Uloženo v:
| Vydáno v: | J Biol Chem |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742755/ https://ncbi.nlm.nih.gov/pubmed/26627826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.683185 |
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