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Inducible Expression of CXCL1 within the Central Nervous System Amplifies Viral-Induced Demyelination

The functional role of the ELR(+) chemokine CXCL1 in host defense and disease following infection of the CNS with the neurotropic JHM strain of mouse hepatitis virus (JHMV) was examined. Mice in which expression of CXCL1 is under the control of a tetracycline-inducible promoter active within glial f...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Marro, Brett S., Grist, Jonathan J., Lane, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742654/
https://ncbi.nlm.nih.gov/pubmed/26773148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501802
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