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Moonlighting metals: insights into regulation of cyclization pathways in fungal Δ6-protoilludene sesquiterpene synthases

Fungal 1,11 cyclizing sesquiterpene synthases are product specific under typical reaction conditions. However, in vivo expression of certain Δ6-protoilludene synthases results in a dual 1,11 and 1,10 cyclization cascade. To determine the factors regulating this mechanistic versatility, in depth char...

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Bibliographic Details
Published in:Chembiochem
Main Authors: Quin, Maureen B., Michel, Stephen N., Schmidt-Dannert, Claudia
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742524/
https://ncbi.nlm.nih.gov/pubmed/26239156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500308
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