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Selectivity of Fungal Sesquiterpene Synthases: Role of the Active Site's H-1α Loop in Catalysis

Sesquiterpene synthases are responsible for the cyclization of farnesyl pyrophosphate into a myriad of structurally diverse compounds with various biological activities. We examine here the role of the conserved active site H-α1 loop in catalysis in three previously characterized fungal sesquiterpen...

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Bibliografski detalji
Glavni autori: López-Gallego, Fernando, Wawrzyn, GraysonT., Schmidt-Dannert, Claudia
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988597/
https://ncbi.nlm.nih.gov/pubmed/20889795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01811-10
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