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G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers
Granulocyte colony-stimulating factor (G-CSF) is an essential regulator of neutrophil trafficking and is highly expressed in multiple tumors. Myeloid derived suppressor cells (MDSCs) promote neoplastic progression through multiple mechanisms by immune suppression. Despite the findings of G-CSF funct...
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| Publicat a: | Protein Cell |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Higher Education Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742385/ https://ncbi.nlm.nih.gov/pubmed/26797765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-015-0237-2 |
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