G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers

Granulocyte colony-stimulating factor (G-CSF) is an essential regulator of neutrophil trafficking and is highly expressed in multiple tumors. Myeloid derived suppressor cells (MDSCs) promote neoplastic progression through multiple mechanisms by immune suppression. Despite the findings of G-CSF funct...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Protein Cell
Main Authors: Li, Wenbin, Zhang, Xinghua, Chen, Yongkang, Xie, Yibin, Liu, Jiancheng, Feng, Qiang, Wang, Yi, Yuan, Wei, Ma, Jie
Format: Artigo
Jezik:Inglês
Izdano: Higher Education Press 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742385/
https://ncbi.nlm.nih.gov/pubmed/26797765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-015-0237-2
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