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The Role of New Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia

Imatinib mesylate was the first tyrosine kinase inhibitor (TKI) approved for the management of chronic myeloid leukemia (CML). Imatinib produces acceptable responses in ~ 60% of patients; with ~20% discontinuing therapy due to intolerance and ~20% developing drug resistance. The advent of newer TKIs...

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Dettagli Bibliografici
Pubblicato in:Cancer J
Autori principali: Pophali, Priyanka A., Patnaik, Mrinal M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742366/
https://ncbi.nlm.nih.gov/pubmed/26841016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000165
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