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The Role of New Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia

Imatinib mesylate was the first tyrosine kinase inhibitor (TKI) approved for the management of chronic myeloid leukemia (CML). Imatinib produces acceptable responses in ~ 60% of patients; with ~20% discontinuing therapy due to intolerance and ~20% developing drug resistance. The advent of newer TKIs...

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Detalhes bibliográficos
Publicado no:Cancer J
Main Authors: Pophali, Priyanka A., Patnaik, Mrinal M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742366/
https://ncbi.nlm.nih.gov/pubmed/26841016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000165
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