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A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy
BACKGROUND: Depending on the epidemiological setting, a variable proportion of leprosy patients will suffer from excessive pro-inflammatory responses, termed type-1 reactions (T1R). The LRRK2 gene encodes a multi-functional protein that has been shown to modulate pro-inflammatory responses. Variants...
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| Vydáno v: | PLoS Negl Trop Dis |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742274/ https://ncbi.nlm.nih.gov/pubmed/26844546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004412 |
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