Augmentation of autologous T cell reactivity with acute myeloid leukemia (AML) blasts by Toll-like receptor (TLR) agonists

This study investigated whether TNF-α, Toll-like receptors (TLRs) 7/8 agonist resiquimod (R848), the TLR4 agonist lipopolysaccharide (LPS) and their combinations can enhance autologous AML-reactive T cell generation in an in vitro culture. AML peripheral blood or bone marrow mononuclear cells were c...

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Vydáno v:Cancer Immunol Immunother
Hlavní autoři: Zhong, RuiKun, Li, Hongying, Messer, Karen, Lane, Thomas A., Zhou, Jiehua, Ball, Edward D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742236/
https://ncbi.nlm.nih.gov/pubmed/25795133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-015-1680-x
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