Adiponectin promotes VEGF-A-dependent angiogenesis in human chondrosarcoma through PI3K, Akt, mTOR, and HIF-α pathway

Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant metastasis. Adiponectin is a protein hormone secreted predominantly by differentiated adipocytes. On the other hand, angiogenesis is a critical step in tumor growth and metastasis. However,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Hsiang-Ping, Lin, Chih-Yang, Shih, Jhao-Sheng, Fong, Yi-Chin, Wang, Shih-Wei, Li, Te-Mao, Tang, Chih-Hsin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742208/
https://ncbi.nlm.nih.gov/pubmed/26468982
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