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CCL5 promotes VEGF-dependent angiogenesis by down-regulating miR-200b through PI3K/Akt signaling pathway in human chondrosarcoma cells

Chondrosarcoma is the second most common primary malignant bone cancer, with potential for local invasion and distant metastasis. Chemokine CCL5 (formerly RANTES) of the CC-chemokine family plays a crucial role in metastasis. Angiogenesis is essential for the cancer metastasis. However, correlation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Liu, Guan-Ting, Chen, Hsien-Te, Tsou, Hsi-Kai, Tan, Tzu-Wei, Fong, Yi-Chin, Chen, Po-Chen, Yang, Wei-Hung, Wang, Shih-Wei, Chen, Jui-Chieh, Tang, Chih-Hsin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279405/
https://ncbi.nlm.nih.gov/pubmed/25301739
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