Overexpression of denticleless E3 ubiquitin protein ligase homolog (DTL) is related to poor outcome in gastric carcinoma

BACKGROUND: Denticleless E3 ubiquitin protein ligase homolog (DTL) has been identified in amplified region (1q32) of several cancers and has an oncogenic function. In this study, we tested whether DTL acts as a cancer-promoting gene through its activation/overexpression in gastric cancer (GC). METHO...

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Publicado en:Oncotarget
Main Authors: Kobayashi, Hiroki, Komatsu, Shuhei, Ichikawa, Daisuke, Kawaguchi, Tsutomu, Hirajima, Shoji, Miyamae, Mahito, Okajima, Wataru, Ohashi, Takuma, Kosuga, Toshiyuki, Konishi, Hirotaka, Shiozaki, Atsushi, Fujiwara, Hitoshi, Okamoto, Kazuma, Tsuda, Hitoshi, Otsuji, Eigo
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742199/
https://ncbi.nlm.nih.gov/pubmed/26472028
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