Frequent DPH3 promoter mutations in skin cancers

Recent reports suggested frequent occurrence of cancer associated somatic mutations within regulatory elements of the genome. Based on initial exome sequencing of 21 melanomas, we report frequent somatic mutations in skin cancers in a bidirectional promoter of diphthamide biosynthesis 3 (DPH3) and o...

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Gepubliceerd in:Oncotarget
Hoofdauteurs: Denisova, Evgeniya, Heidenreich, Barbara, Nagore, Eduardo, Rachakonda, P. Sivaramakrishna, Hosen, Ismail, Akrap, Ivana, Traves, Víctor, García-Casado, Zaida, López-Guerrero, José Antonio, Requena, Celia, Sanmartin, Onofre, Serra-Guillén, Carlos, Llombart, Beatriz, Guillén, Carlos, Ferrando, Jose, Gimeno, Enrique, Nordheim, Alfred, Hemminki, Kari, Kumar, Rajiv
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2015
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742151/
https://ncbi.nlm.nih.gov/pubmed/26416425
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