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A combination of tyrosine kinase inhibitors, crizotinib and dasatinib for the treatment of glioblastoma multiforme

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor. Despite the advances in surgery, radiotherapy and chemotherapy, patient survival averages only 14.6 months. In most GBM tumors, tyrosine kinases show increased activity and/or expression and actively contribute to t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nehoff, Hayley, Parayath, Neha N., McConnell, Melanie J., Taurin, Sebastien, Greish, Khaled
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741976/
https://ncbi.nlm.nih.gov/pubmed/26517812
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