Sorafenib-induced defective autophagy promotes cell death by necroptosis

Autophagy is one of the main cytoprotective mechanisms that cancer cells deploy to withstand the cytotoxic stress and survive the lethal damage induced by anti-cancer drugs. However, under specific conditions, autophagy may, directly or indirectly, induce cell death. In our study, treatment of the A...

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發表在:Oncotarget
Main Authors: Kharaziha, Pedram, Chioureas, Dimitris, Baltatzis, George, Fonseca, Pedro, Rodriguez, Patricia, Gogvadze, Vladimir, Lennartsson, Lena, Björklund, Ann-Charlotte, Zhivotovsky, Boris, Grandér, Dan, Egevad, Lars, Nilsson, Sten, Panaretakis, Theocharis
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
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Research paper: Autophagy and Cell Death
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741916/
https://ncbi.nlm.nih.gov/pubmed/26416459
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