Identification of CD146 as a marker enriched for tumor-propagating capacity reveals targetable pathways in primary human sarcoma

Tumor-propagating cells (TPCs) are believed to drive cancer initiation, progression and recurrence. These cells are characterized by enhanced tumorigenicity and self-renewal. The ability to identify such cells in primary human sarcomas relies on the dye exclusion ability of tumor side population (SP...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wei, Qingxia, Tang, Yuning J., Voisin, Veronique, Sato, Shingo, Hirata, Makoto, Whetstone, Heather, Han, Ilkyu, Ailles, Laurie, Bader, Gary D., Wunder, Jay, Alman, Benjamin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741895/
https://ncbi.nlm.nih.gov/pubmed/26517673
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