Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer

In metastatic breast cancers, the acquisition of metastatic ability, which leads to clinically incurable disease and poor survival, has been associated with acquisition of epithelial-mesenchymal transition (EMT) program and self-renewing trait (CSCs) via activation of PI3K/AKT and IL6/JAK2/STAT3 sig...

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Publicado en:Oncotarget
Autores principales: Kim, Min Soo, Lee, Won Sung, Jeong, Joon, Kim, Seong-Jin, Jin, Wook
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741886/
https://ncbi.nlm.nih.gov/pubmed/26515594
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