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Dysregulated JAK2 expression by TrkC promotes metastasis potential, and EMT program of metastatic breast cancer
Metastatic breast cancers are aggressive tumors associated with high levels of epithelial-mesenchymal transition (EMT) markers, activation of IL6/JAK2/STAT3 and PI3K/AKT pathways for cell growth, mobility, invasion, metastasis, and CSC status. We identified a new molecular and functional network pre...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5032000/ https://ncbi.nlm.nih.gov/pubmed/27654855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33899 |
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