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Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats

Mitochondrial dysfunction plays a central role in the pathogenesis of sarcopenia associated with a loss of mass and activity of skeletal muscle. In addition to energy deprivation, increased mitochondrial ROS damage proteins and lipids in aged skeletal muscle. Therefore, prevention of mitochondrial R...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Javadov, Sabzali, Jang, Sehwan, Rodriguez-Reyes, Natividad, Rodriguez-Zayas, Ana E., Hernandez, Jessica Soto, Krainz, Tanja, Wipf, Peter, Frontera, Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741839/
https://ncbi.nlm.nih.gov/pubmed/26415224
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