EGFRvIII does not affect radiosensitivity with or without gefitinib treatment in glioblastoma cells

BACKGROUND: Glioblastomas (GBM) are often characterized by an elevated expression of the epidermal growth factor receptor variant III (EGFRvIII). We used GBM cell lines with native EGFRvIII expression to determine whether this EGFR variant affects radiosensitivity with or without EGFR targeting. MET...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Struve, Nina, Riedel, Matthias, Schulte, Alexander, Rieckmann, Thorsten, Grob, Tobias J., Gal, Andreas, Rothkamm, Kai, Lamszus, Katrin, Petersen, Cordula, Dikomey, Ekkehard, Kriegs, Malte
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741808/
https://ncbi.nlm.nih.gov/pubmed/26418954
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