Targeting EZH2 regulates tumor growth and apoptosis through modulating mitochondria dependent cell-death pathway in HNSCC

EZH2 is a negative prognostic factor and is overexpressed or activated in most human cancers including head and neck squamous cell carcinoma (HNSCC). Analysis of The Cancer Genome Atlas (TCGA) HNSCC data indicated that EZH2 over-expression was associated with high tumor grade and conferred poor prog...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhou, Xuan, Ren, Yu, Kong, Lingping, Cai, Guoshuai, Sun, Shanshan, Song, Wangzhao, Wang, Yu, Jin, Rui, Qi, Lisha, Mei, Mei, Wang, Xudong, Kang, Chunsheng, Li, Min, Zhang, Lun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741797/
https://ncbi.nlm.nih.gov/pubmed/26378043
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