GRP78 confers the resistance to 5-FU by activating the c-Src/LSF/TS Axis in hepatocellular carcinoma

5-FU is a common first-line chemotherapeutic drug for the treatment of hepatocellular carcinoma. However the development of acquired resistance to 5-FU confines its clinical usages. Although this phenomenon has been the subject of intense investigation, the exact mechanism of acquired resistance to...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gu, Yan-jiao, Li, Hong-dan, Zhao, Liang, Zhao, Song, He, Wu-bin, Rui, Li, Su, Chang, Zheng, Hua-chuan, Su, Rong-jian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741793/
https://ncbi.nlm.nih.gov/pubmed/26378040
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