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Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells

Members of the bromodomain and extra-C terminal (BET) domain protein family and the histone deacetylase (HDAC) enzyme family regulate the expression of important oncogenes and tumor suppressor genes. Here we show that the BET inhibitor JQ1 inhibits proliferation and induces apoptosis of both triple...

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Pubblicato in:Oncotarget
Autori principali: Borbely, Gabor, Haldosen, Lars-Arne, Dahlman-Wright, Karin, Zhao, Chunyan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741790/
https://ncbi.nlm.nih.gov/pubmed/26378038
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