Golgi protein 73 activation of MMP-13 promotes hepatocellular carcinoma cell invasion

Golgi Protein 73 (GP73) is a serum biomarker for hepatocellular carcinoma (HCC), however its role in HCC is not clear. We report that GP73 promotes cell invasion, the hallmark of malignancy, through the upregulation of matrix metalloproteinase-13 (MMP-13). GP73 enhances MMP-13 expression through cAM...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Jin, Di, Tao, Jun, Li, Dan, Wang, Yanan, Li, Li, Hu, Zhongdong, Zhou, Zhenzhen, Chang, Xiuli, Qu, Chunfeng, Zhang, Hongbing
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741783/
https://ncbi.nlm.nih.gov/pubmed/26378022
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