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Golgi protein 73 activation of MMP-13 promotes hepatocellular carcinoma cell invasion

Golgi Protein 73 (GP73) is a serum biomarker for hepatocellular carcinoma (HCC), however its role in HCC is not clear. We report that GP73 promotes cell invasion, the hallmark of malignancy, through the upregulation of matrix metalloproteinase-13 (MMP-13). GP73 enhances MMP-13 expression through cAM...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Jin, Di, Tao, Jun, Li, Dan, Wang, Yanan, Li, Li, Hu, Zhongdong, Zhou, Zhenzhen, Chang, Xiuli, Qu, Chunfeng, Zhang, Hongbing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741783/
https://ncbi.nlm.nih.gov/pubmed/26378022
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