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MT1-MMP dependent repression of the tumor suppressor SPRY4 contributes to MT1-MMP driven melanoma cell motility

Metastatic melanoma is the deadliest of all skin cancers. Despite progress in diagnostics and treatment of melanoma, the prognosis for metastatic patients remains poor. We previously showed that Membrane-type 1 Matrix Metalloproteinase (MT1-MMP) is one of the drivers of melanoma metastasis. Classica...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Shaverdashvili, Khvaramze, Zhang, Keman, Osman, Iman, Honda, Kord, Jobava, Rauli, Bedogni, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741782/
https://ncbi.nlm.nih.gov/pubmed/26392417
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