MT1-MMP recruits the ER-Golgi SNARE Bet1 for efficient MT1-MMP transport to the plasma membrane

Metastasis is a major cause of cancer-related death. Membrane type 1–matrix metalloproteinase (MT1-MMP) is a critical protease for local invasion and metastasis. MT1-MMP is synthesized in the endoplasmic reticulum (ER) and transported in vesicles to invadopodia, specialized subdomains of the plasma...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Miyagawa, Takuya, Hasegawa, Kana, Aoki, Yoko, Watanabe, Takuya, Otagiri, Yuka, Arasaki, Kohei, Wakana, Yuichi, Asano, Kenichi, Tanaka, Masato, Yamaguchi, Hideki, Tagaya, Mitsuo, Inoue, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781441/
https://ncbi.nlm.nih.gov/pubmed/31519727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201808149
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