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Silencing NKD2 by promoter region hypermethylation promotes gastric cancer invasion and metastasis by up-regulating SOX18 in human gastric cancer

Naked cuticle homolog2 (NKD2) is located in chromosome 5p15.3, which is frequently loss of heterozygosity in human colorectal and gastric cancers. In order to understand the mechanism of NKD2 in gastric cancer development, 6 gastric cancer cell lines and 196 cases of human primary gastric cancer sam...

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Publicat a:Oncotarget
Autors principals: Jia, Yan, Cao, Baoping, Yang, Yunsheng, Linghu, Enqiang, Zhan, Qimin, Lu, Youyong, Yu, Yingyan, Herman, James G., Guo, Mingzhou
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741779/
https://ncbi.nlm.nih.gov/pubmed/26396173
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