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Epigenetic silencing of NKD2, a major component of Wnt signaling, promotes breast cancer growth

Naked cuticle homolog 2 (NKD2) has been reported to antagonize Wnt signaling in zebrafish, mouse and mammals. The aim of this study is to investigate the epigenetic changes and mechanisms of NKD2 in human breast cancer development. Six breast cancer cell lines (MCF-7, ZR75-1, MDA-MB-468, MDA-MB-231,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dong, Yan, Cao, Baoping, Zhang, Meiying, Han, Weidong, Herman, James G., Fuks, François, Zhao, Yali, Guo, Mingzhou
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673151/
https://ncbi.nlm.nih.gov/pubmed/26124080
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