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IL-17 producing mast cells promote the expansion of myeloid-derived suppressor cells in a mouse allergy model of colorectal cancer

Food allergy can influence the development of colorectal cancer, although the underlying mechanisms are unclear. While mast cells (MC) store and secrete histamine, immature myeloid cells (IMC) are the major site of histidine decarboxylase (HDC) expression, the enzyme responsible for histamine produc...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Xiaowei, Churchill, Michael J., Nagar, Karan K., Tailor, Yagnesh H., Chu, Timothy, Rush, Brittany S., Jiang, Zhengyu, Wang, Edwin B.C., Renz, Bernhard W., Wang, Hongshan, Fung, Ming Chiu, Worthley, Daniel L., Mukherjee, Siddhartha, Wang, Timothy C.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741743/
https://ncbi.nlm.nih.gov/pubmed/26429861
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