A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials

Chromosome instability (CIN) in solid tumours results in multiple numerical and structural chromosomal aberrations and is associated with poor prognosis in multiple tumour types. Recent evidence demonstrated CEP17 duplication, a CIN marker, is a predictive marker of anthracycline benefit. An analysi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Spears, Melanie, Yousif, Fouad, Lyttle, Nicola, Boutros, Paul C., Munro, Alison F., Twelves, Chris, Pritchard, Kathleen I., Levine, Mark N., Shepherd, Lois, Bartlett, John MS.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741633/
https://ncbi.nlm.nih.gov/pubmed/26372731
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