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Discovery of Compound A – a selective activator of the glucocorticoid receptor with anti-inflammatory and anti-cancer activity

Glucocorticoids are among the most effective anti-inflammatory drugs, and are widely used for cancer therapy. Unfortunately, chronic treatment with glucocorticoids results in multiple side effects. Thus, there was an intensive search for selective glucocorticoid receptor (GR) activators (SEGRA), whi...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Lesovaya, Ekaterina, Yemelyanov, Alexander, Swart, Amanda C., Swart, Pieter, Haegeman, Guy, Budunova, Irina
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741564/
https://ncbi.nlm.nih.gov/pubmed/26436695
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