Combination of a selective activator of the glucocorticoid receptor Compound A with a proteasome inhibitor as a novel strategy for chemotherapy of hematologic malignancies

Glucocorticoids are widely used for the treatment of hematological malignancies; however, their chronic use results in numerous metabolic side effects. Thus, the development of selective glucocorticoid receptor (GR) activators (SEGRA) with improved therapeutic index is important. GR regulates gene e...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lesovaya, Ekaterina, Yemelyanov, Alexander, Kirsanov, Kirill, Popa, Alexander, Belitsky, Gennady, Yakubovskaya, Marianna, Gordon, Leo I., Rosen, Steven T., Budunova, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570502/
https://ncbi.nlm.nih.gov/pubmed/23255118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23048
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados