Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling

Here, we developed an isogenic cell model of “stemness” to facilitate protein biomarker discovery in breast cancer. For this purpose, we used knowledge gained previously from the study of the mouse mammary tumor virus (MMTV). MMTV initiates mammary tumorigenesis in mice by promoter insertion adjacen...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Lamb, Rebecca, Bonuccelli, Gloria, Ozsvári, Béla, Peiris-Pagès, Maria, Fiorillo, Marco, Smith, Duncan L., Bevilacqua, Generoso, Mazzanti, Chiara Maria, McDonnell, Liam A., Naccarato, Antonio Giuseppe, Chiu, Maybo, Wynne, Luke, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Priority Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741544/
https://ncbi.nlm.nih.gov/pubmed/26421711
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