Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling

Here, we developed an isogenic cell model of “stemness” to facilitate protein biomarker discovery in breast cancer. For this purpose, we used knowledge gained previously from the study of the mouse mammary tumor virus (MMTV). MMTV initiates mammary tumorigenesis in mice by promoter insertion adjacen...

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Vydáno v:Oncotarget
Hlavní autoři: Lamb, Rebecca, Bonuccelli, Gloria, Ozsvári, Béla, Peiris-Pagès, Maria, Fiorillo, Marco, Smith, Duncan L., Bevilacqua, Generoso, Mazzanti, Chiara Maria, McDonnell, Liam A., Naccarato, Antonio Giuseppe, Chiu, Maybo, Wynne, Luke, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Priority Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741544/
https://ncbi.nlm.nih.gov/pubmed/26421711
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