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Convergence of cMyc and β‐catenin on Tcf7l1 enables endoderm specification
The molecular machinery that directs formation of definitive endoderm from pluripotent stem cells is not well understood. Wnt/β‐catenin and Nodal signalling have been implicated, but the requirements for lineage specification remain incompletely defined. Here, we demonstrate a potent effect of inhib...
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Publicado no: | EMBO J |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4741304/ https://ncbi.nlm.nih.gov/pubmed/26675138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592116 |
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