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Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling

Receptor organization and dynamics at the cell membrane are important factors of signal transduction regulation. Using super‐resolution microscopy and single‐particle tracking, we show how the negative coreceptor CD22 works with the cortical cytoskeleton in restraining BCR signalling. In naïve B cel...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Gasparrini, Francesca, Feest, Christoph, Bruckbauer, Andreas, Mattila, Pieta K, Müller, Jennifer, Nitschke, Lars, Bray, Dennis, Batista, Facundo D
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741297/
https://ncbi.nlm.nih.gov/pubmed/26671981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593027
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