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miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability
The evolutionarily conserved miR-302 family of microRNAs is expressed during early mammalian embryonic development. Here, we report that deletion of miR-302a-d in mice results in a fully penetrant late embryonic lethal phenotype. Knockout embryos have an anterior neural tube closure defect associate...
Shranjeno v:
| izdano v: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4741278/ https://ncbi.nlm.nih.gov/pubmed/26212322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.074 |
| Oznake: |
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