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Crystallization and X-ray diffraction of LGN in complex with the actin-binding protein afadin

Asymmetric stem-cell divisions are fundamental for morphogenesis and tissue homeostasis. They rely on the coordination between cortical polarity and the orientation of the mitotic spindle, which is orchestrated by microtubule pulling motors recruited at the cortex by NuMA–LGN–Gαi complexes. LGN has...

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Veröffentlicht in:Acta Crystallogr F Struct Biol Commun
Hauptverfasser: Carminati, Manuel, Cecatiello, Valentina, Mapelli, Marina
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741196/
https://ncbi.nlm.nih.gov/pubmed/26841766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16000807
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